Chemoprevention in Barrett's Esophagus: Are We There Yet, Are We There Yet…?

This is perhaps the most commonly asked question from patients after they receive a Barrett's esophagus diagnosis, and one of the most challenging to answer. Chemoprevention, the use of pharmacologic agents or supplements to modify cancer risk, is an area of intense interest given the relative ease of administration. If effective, chemoprevention could be doubly appealing: it could both diminish cancer risk and decrease (or eliminate) the need for invasive, costly endoscopic procedures used for surveillance and treatment of Barrett's esophagus or dysplasia.